es | en | fr | it

PICSI (Sperm Low)

What is PICSI?

The PICSI method is a physiological variation on the ICSI technique (sperm microinjection), which is performed using hyaluronic acid (HA). Hyaluronic acid is involved in the sperm selection mechanism: only mature spermatozoids that have their specific receptors out can bind to the HA around the outer membrane of the egg and fertilise it.

With traditional ICSI, sperm selection is performed by embryologist observation. Physiological ICSI, or PICSI, is less subjective and helps to optimise the results of assisted reproduction treatment.

PICSI (Sperm Low) | URE Centro Gutenberg

When is PICSI (Sperm Low) indicated?

PICSI is very useful in patients with high sperm DNA fragmentation but good sperm motility, as the technique helps to select the best quality mature spermatozoids.

These spermatozoids are individually selected and have low fragmentation levels, thus decreasing the likelihood of chromosome abnormalities.

Keeping in mind that this is an experimental technique which is still being researched, it is difficult to determine which patients it is indicated for. But, generally speaking, it is indicated in the following cases:

N

Elevated sperm DNA fragmentation levels

N

Previous IVF-ICSI failure, with poor embryo quality

N

Unexplained infertility

N

Couples with recurrent miscarriage likely due to male factor infertility

N

Abnormal sperm FISH analysis

N

Repeated implantation failure

PICSI (Sperm Low) Procedure

The sperm sample for PICSI is collected as usual. After sperm capacitation, the spermatozoids are placed on a special slide.

This slide contains drops of a synthetic material which closely resembles the hyaluronic acid that naturally surrounds oocytes. Good quality spermatozoids will bind to these drops, so the embryologist will be able to easily identify them.

Once the spermatozoid has been selected it is aspirated with the microinjection pipette and ICSI is performed as usual.

More info

Complete the form or call us at (+34) 952 122 565.

In accordance with that established by current regulations on Personal Data Protection, we inform you that your personal data will be used by CENTRO GUTENBERG REPRODUCTION LABORATORY, S.L., which is responsible for handling this data in order to manage the information requests received through web forms and social networks. Likewise, we inform you that your data will not be disclosed to third parties, except in the event of a legal obligation or if we have your express consent.

You are entitled to obtain confirmation about whether we are using your personal data, and are thus entitled to access your personal data, rectify inaccurate data or request its elimination if the data is no longer necessary; you are also entitled to exercise all other rights under the regulation, as explained in the additional information. You may exercise the indicated rights in accordance with the terms established by current regulations by writing to: LABORATORIO DE REPRODUCCIÓN CENTRO GUTENBERG, S.L., C/ Gutenberg, nº 5, 29016 MÁLAGA (SPAIN), e mail: administración@urecentrogutenberg.com. Additionally, you may request additional, detailed information regarding our data protection policy via the same contact information. You may consult our additional information by clicking here