{"id":39560,"date":"2025-06-23T12:57:39","date_gmt":"2025-06-23T10:57:39","guid":{"rendered":"https:\/\/urecentrogutenberg.es\/chronic-endometritis-symptoms-and-treatment\/"},"modified":"2025-06-23T12:57:39","modified_gmt":"2025-06-23T10:57:39","slug":"chronic-endometritis-symptoms-and-treatment","status":"publish","type":"post","link":"https:\/\/urecentrogutenberg.es\/en\/chronic-endometritis-symptoms-and-treatment\/","title":{"rendered":"Chronic endometritis: symptoms and treatment"},"content":{"rendered":"<p>Chronic endometritis is a long-lasting infection that is characterised by\u00a0<strong>persistent inflammation of the endometrial tissue<\/strong>\u00a0that lines the uterine cavity.<\/p>\n<p>It\u2019s difficult to quantify the incidence and prevalence of chronic endometritis. This is due to the fact that several uterine issues such as\u00a0<a href=\"https:\/\/urecentrogutenberg.es\/en\/myomas-and-their-implications-on-female-infertility\/\" target=\"_blank\" rel=\"noopener\"><strong>submucosal fibroids<\/strong><\/a>,\u00a0<a href=\"https:\/\/fertilityclinicspain.com\/what-are-endometrial-polyps-and-their-relationship-with-infertility\/\" target=\"_blank\" rel=\"noopener\"><strong>endometrial polyps<\/strong><\/a>, endometrial hyperplasia, etc., also increase the likelihood of suffering from chronic endometritis. However, the primary cause of chronic endometritis is infection caused by microorganisms in the uterine cavity, mainly bacteria.<\/p>\n<p>In this regard, there are different risk factors which may encourage this infection to appear and develop such as using an IUD, suffering a miscarriage with or without dilation and curettage, the presence of abnormal uterine bleeding,\u00a0<strong>obstruction of a Fallopian tube<\/strong>\u00a0or having already carried several pregnancies to term, etc.<\/p>\n<p>In this article we\u2019re going to talk to you more about chronic endometritis as well as\u00a0<strong>what the symptoms are and what treatment options are available<\/strong>.<\/p>\n<div id=\"ez-toc-container\" class=\"ez-toc-v2_0_85 counter-hierarchy ez-toc-counter ez-toc-custom ez-toc-container-direction\">\n<div class=\"ez-toc-title-container\">\n<p class=\"ez-toc-title\" style=\"cursor:inherit\">Tabla de contenidos<\/p>\n<span class=\"ez-toc-title-toggle\"><a href=\"#\" class=\"ez-toc-pull-right ez-toc-btn ez-toc-btn-xs ez-toc-btn-default ez-toc-toggle\" aria-label=\"Toggle Table of Content\"><span class=\"ez-toc-js-icon-con\"><span class=\"\"><span class=\"eztoc-hide\" style=\"display:none;\">Toggle<\/span><span class=\"ez-toc-icon-toggle-span\"><svg style=\"fill: #3f3f3f;color:#3f3f3f\" xmlns=\"http:\/\/www.w3.org\/2000\/svg\" class=\"list-377408\" width=\"20px\" height=\"20px\" viewBox=\"0 0 24 24\" fill=\"none\"><path d=\"M6 6H4v2h2V6zm14 0H8v2h12V6zM4 11h2v2H4v-2zm16 0H8v2h12v-2zM4 16h2v2H4v-2zm16 0H8v2h12v-2z\" fill=\"currentColor\"><\/path><\/svg><svg style=\"fill: #3f3f3f;color:#3f3f3f\" class=\"arrow-unsorted-368013\" xmlns=\"http:\/\/www.w3.org\/2000\/svg\" width=\"10px\" height=\"10px\" viewBox=\"0 0 24 24\" version=\"1.2\" baseProfile=\"tiny\"><path d=\"M18.2 9.3l-6.2-6.3-6.2 6.3c-.2.2-.3.4-.3.7s.1.5.3.7c.2.2.4.3.7.3h11c.3 0 .5-.1.7-.3.2-.2.3-.5.3-.7s-.1-.5-.3-.7zM5.8 14.7l6.2 6.3 6.2-6.3c.2-.2.3-.5.3-.7s-.1-.5-.3-.7c-.2-.2-.4-.3-.7-.3h-11c-.3 0-.5.1-.7.3-.2.2-.3.5-.3.7s.1.5.3.7z\"\/><\/svg><\/span><\/span><\/span><\/a><\/span><\/div>\n<nav><ul class='ez-toc-list ez-toc-list-level-1 ' ><li class='ez-toc-page-1 ez-toc-heading-level-2'><a class=\"ez-toc-link ez-toc-heading-1\" href=\"https:\/\/urecentrogutenberg.es\/en\/chronic-endometritis-symptoms-and-treatment\/#How_chronic_endometritis_and_infertility_are_related\" >How chronic endometritis and infertility are related<\/a><\/li><li class='ez-toc-page-1 ez-toc-heading-level-2'><a class=\"ez-toc-link ez-toc-heading-2\" href=\"https:\/\/urecentrogutenberg.es\/en\/chronic-endometritis-symptoms-and-treatment\/#Symptoms_and_diagnosis_of_chronic_endometritis\" >Symptoms and diagnosis of chronic endometritis<\/a><\/li><li class='ez-toc-page-1 ez-toc-heading-level-2'><a class=\"ez-toc-link ez-toc-heading-3\" href=\"https:\/\/urecentrogutenberg.es\/en\/chronic-endometritis-symptoms-and-treatment\/#Treatment_for_chronic_endometritis\" >Treatment for chronic endometritis<\/a><\/li><\/ul><\/nav><\/div>\n<h2><span class=\"ez-toc-section\" id=\"How_chronic_endometritis_and_infertility_are_related\"><\/span>How chronic endometritis and infertility are related<span class=\"ez-toc-section-end\"><\/span><\/h2>\n<p>Chronic endometritis is a<strong>\u00a0silent illness<\/strong><strong>\u00a0that is present in a certain percentage of females who are not able to conceive naturally<\/strong>.<\/p>\n<p>Different studies have shown that chronic endometritis may be prevalent in females with fertility issues, especially in those who have been\u00a0<strong>diagnosed with\u00a0<\/strong><strong>implantation failure<\/strong>. In other words, in women who have undergone several cycles of IVF treatment (specifically, more than two unsuccessful embryo transfers), but who have not been able to conceive.<\/p>\n<p>Investigations that have been carried out explain that chronic endometritis\u00a0<strong>could disrupt what we call the \u201cwindow of implantation\u201d<\/strong>, which is the ideal period of time for embryo implantation to correctly take place in the endometrium. If the window of implantation is disturbed, endometrial receptivity will be lower. This disruption has also been associated with recurrent miscarriage and complications during pregnancy.<\/p>\n<h2><span class=\"ez-toc-section\" id=\"Symptoms_and_diagnosis_of_chronic_endometritis\"><\/span>Symptoms and diagnosis of chronic endometritis<span class=\"ez-toc-section-end\"><\/span><\/h2>\n<p>Generally speaking, when we talk about the symptoms of chronic endometritis we may encounter cases in which the female is\u00a0<strong>asymptomatic or has very mild symptoms\u00a0<\/strong>such as uterine bleeding, certain pelvic discomfort or abnormal vaginal discharge.<\/p>\n<p>Having said this, the most reliable way to diagnose chronic endometritis is via an endometrial biopsy which allows us to\u00a0<strong>study hystopathology, and\/or an endometrial culture<\/strong>. In the histology study, the main finding, in order to diagnose chronic endometritis, is the presence of plasmocytes. The immunohistochemistry study focuses on the presence of the CD138 marker, which is one of the most sensitive markers for endometritis.<\/p>\n<p>It is also possible to suspect the existence of chronic endometritis by observing the image of the endometrial cavity that is obtained during a\u00a0<a href=\"https:\/\/urecentrogutenberg.es\/en\/diagnostic-hysteroscopy-in-assisted-reproduction\/\" target=\"_blank\" rel=\"noopener\"><strong>diagnostic hysteroscopy<\/strong><\/a>; characteristic images include micropolyps and endometrial mucous that has the appearance of a \u201cstrawberry\u201d.<\/p>\n<p>These findings may be present in over 40% of patients with a diagnosis of implantation failure or recurrent miscarriage, and in\u00a0<strong>one out of every four women with unexplained infertility<\/strong>.<\/p>\n<h2><span class=\"ez-toc-section\" id=\"Treatment_for_chronic_endometritis\"><\/span>Treatment for chronic endometritis<span class=\"ez-toc-section-end\"><\/span><\/h2>\n<p>Despite the incidence of chronic endometritis, it\u2019s fortunately straightforward to manage, and treatment is successful in the majority of cases.\u00a0<strong>Over 80% of patients are cured<\/strong>\u00a0after taking the appropriate course of antibiotics.<\/p>\n<p><strong>The most commonly prescribed antibiotic for chronic endometritis is doxycycline<\/strong>, which should be taken for fourteen days. Cases of resistant endometritis are treated with ciprofloxacin and metronidazole, also for fourteen days.<\/p>\n<p>Fortunately for women who have this condition and are trying to get pregnant, treating this chronic inflammation -in patients diagnosed with implantation failure- could\u00a0<strong>improve results such as their chances of conceiving and development of a viable pregnancy<\/strong>. On the other hand, not treating chronic endometritis is inevitably associated with lower success rates in assisted reproduction treatment.<\/p>\n<p>&nbsp;<\/p>\n<p>That\u2019s why at URE Centro Gutenberg we suggest discussing your particular case with a specialist in reproductive medicine if you know you have, or think you might have, this ailment.\u00a0<a href=\"https:\/\/urecentrogutenberg.es\/en\/contact\/\" target=\"_blank\" rel=\"noopener\"><strong>Request your appointment with us<\/strong><\/a>\u00a0and we\u2019ll be happy to help you.<\/p>\n","protected":false},"excerpt":{"rendered":"<p>Chronic endometritis is a long-lasting infection that is characterised by\u00a0persistent inflammation of the endometrial tissue\u00a0that lines the uterine cavity. It\u2019s difficult to quantify the incidence and prevalence of chronic endometritis. This is due to the fact that several uterine issues such as\u00a0submucosal fibroids,\u00a0endometrial polyps, endometrial hyperplasia, etc., also increase the likelihood of suffering from chronic [&hellip;]<\/p>\n","protected":false},"author":2,"featured_media":35012,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"_et_pb_use_builder":"","_et_pb_old_content":"","_et_gb_content_width":"","footnotes":""},"categories":[497],"tags":[538,552,512,529,543,550,622,542,621,623,519,531,518,508,513,503,541,510,506,535,515,505],"class_list":["post-39560","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-fertility-problems","tag-artificial-insemination","tag-artificial-insemination-malaga","tag-assisted-reproduction-clinic-in-malaga","tag-causes-of-infertility","tag-centro-gutenberg-en","tag-centro-gutenberg-malaga-en","tag-chronic-endometritis","tag-clinic-gutenberg-en","tag-endometritis-en","tag-endometritis-and-infertility","tag-female-fertility","tag-fertility","tag-fertility-clinic","tag-fertility-clinic-in-malaga","tag-fertility-treatments-in-malaga","tag-in-vitro-fertilisation","tag-infertility","tag-ivf-clinic-in-malaga","tag-pregnancy","tag-reproduction-unit-gutenberg-centre","tag-reproductive-treatments","tag-ure-centro-gutenberg-en"],"_links":{"self":[{"href":"https:\/\/urecentrogutenberg.es\/en\/wp-json\/wp\/v2\/posts\/39560","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/urecentrogutenberg.es\/en\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/urecentrogutenberg.es\/en\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/urecentrogutenberg.es\/en\/wp-json\/wp\/v2\/users\/2"}],"replies":[{"embeddable":true,"href":"https:\/\/urecentrogutenberg.es\/en\/wp-json\/wp\/v2\/comments?post=39560"}],"version-history":[{"count":2,"href":"https:\/\/urecentrogutenberg.es\/en\/wp-json\/wp\/v2\/posts\/39560\/revisions"}],"predecessor-version":[{"id":40307,"href":"https:\/\/urecentrogutenberg.es\/en\/wp-json\/wp\/v2\/posts\/39560\/revisions\/40307"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/urecentrogutenberg.es\/en\/wp-json\/wp\/v2\/media\/35012"}],"wp:attachment":[{"href":"https:\/\/urecentrogutenberg.es\/en\/wp-json\/wp\/v2\/media?parent=39560"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/urecentrogutenberg.es\/en\/wp-json\/wp\/v2\/categories?post=39560"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/urecentrogutenberg.es\/en\/wp-json\/wp\/v2\/tags?post=39560"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}