{"id":39438,"date":"2025-06-19T10:25:51","date_gmt":"2025-06-19T08:25:51","guid":{"rendered":"https:\/\/urecentrogutenberg.es\/ovitrelle-and-ovidrelle-what-are-they-and-what-are-they-used-for-in-assisted-reproduction\/"},"modified":"2025-11-13T13:52:07","modified_gmt":"2025-11-13T12:52:07","slug":"ovitrelle-and-ovidrelle-what-are-they-and-what-are-they-used-for-in-assisted-reproduction","status":"publish","type":"post","link":"https:\/\/urecentrogutenberg.es\/en\/ovitrelle-and-ovidrelle-what-are-they-and-what-are-they-used-for-in-assisted-reproduction\/","title":{"rendered":"Ovitrelle and Ovidrelle: what are they and what are they used for in assisted reproduction?"},"content":{"rendered":"<p>Ovitrelle\/Ovidrelle are hormones called chorionic gonadotropins (HCG) which we use in assisted reproduction treatment to trigger ovulation.<\/p>\n<div id=\"ez-toc-container\" class=\"ez-toc-v2_0_85 counter-hierarchy ez-toc-counter ez-toc-custom ez-toc-container-direction\">\n<div class=\"ez-toc-title-container\">\n<p class=\"ez-toc-title\" style=\"cursor:inherit\">Tabla de contenidos<\/p>\n<span class=\"ez-toc-title-toggle\"><a href=\"#\" class=\"ez-toc-pull-right ez-toc-btn ez-toc-btn-xs ez-toc-btn-default ez-toc-toggle\" aria-label=\"Toggle Table of Content\"><span class=\"ez-toc-js-icon-con\"><span class=\"\"><span class=\"eztoc-hide\" style=\"display:none;\">Toggle<\/span><span class=\"ez-toc-icon-toggle-span\"><svg style=\"fill: #3f3f3f;color:#3f3f3f\" xmlns=\"http:\/\/www.w3.org\/2000\/svg\" class=\"list-377408\" width=\"20px\" height=\"20px\" viewBox=\"0 0 24 24\" fill=\"none\"><path d=\"M6 6H4v2h2V6zm14 0H8v2h12V6zM4 11h2v2H4v-2zm16 0H8v2h12v-2zM4 16h2v2H4v-2zm16 0H8v2h12v-2z\" fill=\"currentColor\"><\/path><\/svg><svg style=\"fill: #3f3f3f;color:#3f3f3f\" class=\"arrow-unsorted-368013\" xmlns=\"http:\/\/www.w3.org\/2000\/svg\" width=\"10px\" height=\"10px\" viewBox=\"0 0 24 24\" version=\"1.2\" baseProfile=\"tiny\"><path d=\"M18.2 9.3l-6.2-6.3-6.2 6.3c-.2.2-.3.4-.3.7s.1.5.3.7c.2.2.4.3.7.3h11c.3 0 .5-.1.7-.3.2-.2.3-.5.3-.7s-.1-.5-.3-.7zM5.8 14.7l6.2 6.3 6.2-6.3c.2-.2.3-.5.3-.7s-.1-.5-.3-.7c-.2-.2-.4-.3-.7-.3h-11c-.3 0-.5.1-.7.3-.2.2-.3.5-.3.7s.1.5.3.7z\"\/><\/svg><\/span><\/span><\/span><\/a><\/span><\/div>\n<nav><ul class='ez-toc-list ez-toc-list-level-1 ' ><li class='ez-toc-page-1 ez-toc-heading-level-2'><a class=\"ez-toc-link ez-toc-heading-1\" href=\"https:\/\/urecentrogutenberg.es\/en\/ovitrelle-and-ovidrelle-what-are-they-and-what-are-they-used-for-in-assisted-reproduction\/#What_is_OvitrelleOvidrelle_based_on\" >What is Ovitrelle\/Ovidrelle based on?<\/a><\/li><li class='ez-toc-page-1 ez-toc-heading-level-2'><a class=\"ez-toc-link ez-toc-heading-2\" href=\"https:\/\/urecentrogutenberg.es\/en\/ovitrelle-and-ovidrelle-what-are-they-and-what-are-they-used-for-in-assisted-reproduction\/#Why_do_we_use_OvitrelleOvidrelle_in_assisted_reproduction\" >Why do we use Ovitrelle\/Ovidrelle in assisted reproduction?<\/a><\/li><li class='ez-toc-page-1 ez-toc-heading-level-2'><a class=\"ez-toc-link ez-toc-heading-3\" href=\"https:\/\/urecentrogutenberg.es\/en\/ovitrelle-and-ovidrelle-what-are-they-and-what-are-they-used-for-in-assisted-reproduction\/#How_and_when_are_OvitrelleOvidrelle_administered\" >How and when are Ovitrelle\/Ovidrelle administered?<\/a><\/li><\/ul><\/nav><\/div>\n<h2><span class=\"ez-toc-section\" id=\"What_is_OvitrelleOvidrelle_based_on\"><\/span>What is Ovitrelle\/Ovidrelle based on?<span class=\"ez-toc-section-end\"><\/span><\/h2>\n<p>The\u00a0<a href=\"https:\/\/urecentrogutenberg.es\/en\/what-are-the-main-phases-of-the-menstrual-cycle\/\" target=\"_blank\" rel=\"noopener\">menstrual cycle<\/a>, follicle development and ovulation are all regulated by the production of different hormones\u00a0(FSH and LH) in the pituitary gland.<\/p>\n<p><strong>Changes in the production of these hormones are what cause the different stages of the menstrual cycle<\/strong>: the proliferative phase, ovulation, the secretory phase, and finally menstruation.<\/p>\n<p>At the same time, the ovary produces oestrogen and progesterone in varying amounts depending on what stage of the menstrual cycle the female is currently in.<\/p>\n<p>As a dominant follicle develops (this is the follicle selected by the ovary thanks to the hormones produced in the pituitary gland), it releases oestrogen; then, once the amount of oestrogen reaches a certain level, production of the hormone LH is stimulated in the pituitary gland.<\/p>\n<p>A rapid surge in LH levels triggers final maturation of the egg, rupture of the follicle and then\u00a0<a href=\"https:\/\/urecentrogutenberg.es\/en\/ovulation-why-its-important-to-know-when-it-takes-place-in-assisted-reproduction\/\" target=\"_blank\" rel=\"noopener\">ovulation.<\/a><\/p>\n<p>After ovulation, the female enters into the secretory or luteal phase which is characterised by the production of progesterone by the corpus luteum in the ovary. Oestrogen production continues as well, but in smaller amounts.<\/p>\n<p>While all of the above is taking place,\u00a0the production of oestrogen and progesterone in the ovaries\u00a0prepares the endometrium to become receptive so that a future embryo could potentially implant.<\/p>\n<h2><span class=\"ez-toc-section\" id=\"Why_do_we_use_OvitrelleOvidrelle_in_assisted_reproduction\"><\/span>Why do we use Ovitrelle\/Ovidrelle in assisted reproduction?<span class=\"ez-toc-section-end\"><\/span><\/h2>\n<p>With certain assisted reproduction techniques such as\u00a0<a href=\"https:\/\/urecentrogutenberg.es\/en\/artificial-insemination-frequently-asked-questions-about-this-assisted-reproduction-treatment\/\" target=\"_blank\" rel=\"noopener\">artificial insemination<\/a>\u00a0and\u00a0<a href=\"https:\/\/urecentrogutenberg.es\/en\/in-vitro-fertilisation\/\" target=\"_blank\" rel=\"noopener\">in vitro fertilisation<\/a>,\u00a0<strong>we need to simulate the different phases of an ovulating female\u2019s menstrual cycle<\/strong>.<\/p>\n<p>In order to do so, we generally<a href=\"https:\/\/urecentrogutenberg.es\/en\/ovarian-stimulation-in-assisted-reproduction-we-answer-your-most-frequently-asked-questions\/\" target=\"_blank\" rel=\"noopener\">\u00a0<strong>stimulate the development of one or more follicles in the ovaries<\/strong><\/a><strong>\u00a0via the administration of external FSH<\/strong>; then, when we need to trigger ovulation, we should simulate the natural LH surge.<\/p>\n<p>The amount of the hormone LH needed to simulate this surge is very high, and it\u2019s also very costly.<\/p>\n<p>To simulate the surge, we use a hormone called hCG that is very similar to the hormone LH which is naturally present in the female body.<\/p>\n<p><strong>Administering hCG allows us to have control over the moment when final\u00a0maturation of the\u00a0developed follicles\u00a0will occur<\/strong>, and in turn allows us to schedule the exact day of the<a href=\"https:\/\/urecentrogutenberg.es\/en\/the-egg-retrieval-process-step-by-step\/\" target=\"_blank\" rel=\"noopener\">\u00a0egg retrieval<\/a>\u00a0in IVF\/ICSI treatment, or the day of the intrauterine artificial insemination procedure.<\/p>\n<p>We also often use hCG to trigger ovulation in scheduled sexual intercourse treatment cycles, as well as in preparation cycles for\u00a0<a href=\"https:\/\/urecentrogutenberg.es\/en\/frozen-embryo-transfer-frequently-asked\/\" target=\"_blank\" rel=\"noopener\">frozen embryo transfers<\/a>\u00a0(natural cycle embryo transfers).<\/p>\n<h2><span class=\"ez-toc-section\" id=\"How_and_when_are_OvitrelleOvidrelle_administered\"><\/span><strong>How and when are Ovitrelle\/Ovidrelle administered?<\/strong><span class=\"ez-toc-section-end\"><\/span><\/h2>\n<p><strong>Ovitrelle and Ovidrelle are subcutaneous injections that can be self-administered by patients themselves<\/strong>.<\/p>\n<p>It\u2019s very\u00a0important to administer this medication on the correct day and time, as its timing directly impacts the beginning of a trigger effect which will result in the final maturation of the developing follicles and the egg inside each one.<\/p>\n<p>Moreover, for example, with in vitro fertilisation it would be very unlikely to successfully collect any eggs during an egg retrieval if this medication is not administered correctly or not administered at all.<\/p>\n<p><strong>The\u00a0hormone hCG\u00a0should be administered approximately 36 hours before the egg retrieval procedure is to take place<\/strong>.<\/p>\n<p>Once hCG has triggered ovulation,\u00a0this hormone will also sustain and stimulate the activity of the corpus luteum -the name given to an ovarian follicle after ovulation has occurred-, so that it produces the right levels of progesterone\u00a0which are necessary for correct development of the endometrial lining and for good endometrial receptivity for embryo implantation.<\/p>\n<p>Do you have additional questions or doubts about this hormone that weren\u2019t answered in this article?\u00a0Don\u2019t worry!<\/p>\n<p>Write to us at\u00a0<a href=\"https:\/\/urecentrogutenberg.es\/en\/contact\/\" target=\"_blank\" rel=\"noopener\">here<\/a>\u00a0and we\u2019ll reply to you, cost and commitment-free.<\/p>\n<p>We\u2019ll be happy to help!<\/p>\n","protected":false},"excerpt":{"rendered":"<p>Ovitrelle\/Ovidrelle are hormones called chorionic gonadotropins (HCG) which we use in assisted reproduction treatment to trigger ovulation. What is Ovitrelle\/Ovidrelle based on? The\u00a0menstrual cycle, follicle development and ovulation are all regulated by the production of different hormones\u00a0(FSH and LH) in the pituitary gland. Changes in the production of these hormones are what cause the different [&hellip;]<\/p>\n","protected":false},"author":2,"featured_media":34241,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"_et_pb_use_builder":"","_et_pb_old_content":"","_et_gb_content_width":"","footnotes":""},"categories":[498,537],"tags":[],"class_list":["post-39438","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-frequently-asked-questions-fertility-and-assisted-reproduction","category-miscellaneous"],"_links":{"self":[{"href":"https:\/\/urecentrogutenberg.es\/en\/wp-json\/wp\/v2\/posts\/39438","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/urecentrogutenberg.es\/en\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/urecentrogutenberg.es\/en\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/urecentrogutenberg.es\/en\/wp-json\/wp\/v2\/users\/2"}],"replies":[{"embeddable":true,"href":"https:\/\/urecentrogutenberg.es\/en\/wp-json\/wp\/v2\/comments?post=39438"}],"version-history":[{"count":2,"href":"https:\/\/urecentrogutenberg.es\/en\/wp-json\/wp\/v2\/posts\/39438\/revisions"}],"predecessor-version":[{"id":39719,"href":"https:\/\/urecentrogutenberg.es\/en\/wp-json\/wp\/v2\/posts\/39438\/revisions\/39719"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/urecentrogutenberg.es\/en\/wp-json\/wp\/v2\/media\/34241"}],"wp:attachment":[{"href":"https:\/\/urecentrogutenberg.es\/en\/wp-json\/wp\/v2\/media?parent=39438"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/urecentrogutenberg.es\/en\/wp-json\/wp\/v2\/categories?post=39438"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/urecentrogutenberg.es\/en\/wp-json\/wp\/v2\/tags?post=39438"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}