{"id":32789,"date":"2021-01-20T16:26:43","date_gmt":"2021-01-20T16:26:43","guid":{"rendered":"http:\/\/urecentrogutenberg.es\/picsi-sperm-low\/"},"modified":"2024-06-10T16:41:19","modified_gmt":"2024-06-10T14:41:19","slug":"picsi-sperm-low","status":"publish","type":"page","link":"https:\/\/urecentrogutenberg.es\/en\/picsi-sperm-low\/","title":{"rendered":"PICSI (Sperm Low)"},"content":{"rendered":"<p>[et_pb_section fb_built=&#8221;1&#8243; custom_padding_last_edited=&#8221;on|phone&#8221; admin_label=&#8221;Hero&#8221; _builder_version=&#8221;4.16&#8243; use_background_color_gradient=&#8221;on&#8221; background_color_gradient_stops=&#8221;rgba(77,185,211,0.7) 0%|#4db9d3 100%&#8221; background_color_gradient_overlays_image=&#8221;on&#8221; background_color_gradient_start=&#8221;rgba(77,185,211,0.7)&#8221; background_color_gradient_end=&#8221;#4db9d3&#8243; background_image=&#8221;http:\/\/urecentrogutenberg.es\/wp-content\/uploads\/2020\/05\/tratamientos-tecnicas-ure-centro-gutenberg.jpg&#8221; custom_margin=&#8221;|5vw||&#8221; custom_padding=&#8221;4vw||4vw||true|false&#8221; custom_padding_tablet=&#8221;100px||100px|&#8221; custom_padding_phone=&#8221;|||&#8221; animation_direction=&#8221;left&#8221; border_radii=&#8221;off|||10vw|&#8221; border_color_right=&#8221;#67c1d3&#8243; box_shadow_style=&#8221;preset4&#8243; box_shadow_horizontal=&#8221;20px&#8221; box_shadow_vertical=&#8221;0px&#8221; box_shadow_color=&#8221;rgba(126,196,213,0.8)&#8221; global_colors_info=&#8221;{}&#8221;][et_pb_row _builder_version=&#8221;4.16&#8243; custom_padding=&#8221;0|0px|0px|0px|false|false&#8221; global_colors_info=&#8221;{}&#8221;][et_pb_column type=&#8221;4_4&#8243; _builder_version=&#8221;4.16&#8243; custom_padding=&#8221;|||&#8221; global_colors_info=&#8221;{}&#8221; custom_padding__hover=&#8221;|||&#8221;][et_pb_text admin_label=&#8221;Text&#8221; _builder_version=&#8221;4.16&#8243; text_font=&#8221;Montserrat|300|||||||&#8221; text_font_size=&#8221;22px&#8221; text_line_height=&#8221;1.8em&#8221; 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custom_margin=&#8221;||||false|false&#8221; custom_padding=&#8221;3vw||3vw||true|false&#8221; locked=&#8221;off&#8221; global_colors_info=&#8221;{}&#8221;][et_pb_row column_structure=&#8221;1_2,1_2&#8243; _builder_version=&#8221;4.16&#8243; width=&#8221;100%&#8221; max_width=&#8221;100%&#8221; custom_margin=&#8221;||||true&#8221; custom_margin_tablet=&#8221;||0px|&#8221; custom_margin_phone=&#8221;||||false|true&#8221; custom_margin_last_edited=&#8221;on|phone&#8221; custom_padding=&#8221;0px||0px||true|false&#8221; use_custom_width=&#8221;on&#8221; width_unit=&#8221;off&#8221; custom_width_percent=&#8221;100%&#8221; global_colors_info=&#8221;{}&#8221;][et_pb_column type=&#8221;1_2&#8243; _builder_version=&#8221;4.16&#8243; background_enable_color=&#8221;off&#8221; custom_padding=&#8221;1vw|1vw|4vw|12vw|false|false&#8221; custom_padding_tablet=&#8221;|4vw||4vw|false|false&#8221; custom_padding_phone=&#8221;&#8221; custom_padding_last_edited=&#8221;on|tablet&#8221; global_colors_info=&#8221;{}&#8221; padding_tablet=&#8221;0px|50px|50px|50px&#8221; padding_last_edited=&#8221;on|desktop&#8221; custom_padding__hover=&#8221;|||&#8221; padding_phone=&#8221;0px|50px|50px|50px&#8221;][et_pb_text _builder_version=&#8221;4.16&#8243; text_font=&#8221;Montserrat|300|||||||&#8221; text_line_height=&#8221;1.8em&#8221; header_font=&#8221;||||||||&#8221; header_2_font=&#8221;|300|||||||&#8221; header_2_font_size=&#8221;40px&#8221; header_2_line_height=&#8221;1.5em&#8221; max_width=&#8221;100%&#8221; max_width_tablet=&#8221;100%&#8221; max_width_last_edited=&#8221;off|phone&#8221; custom_margin=&#8221;|||&#8221; custom_margin_tablet=&#8221;0px|50px||50px&#8221; custom_margin_last_edited=&#8221;off|desktop&#8221; custom_padding=&#8221;|||&#8221; header_2_font_size_tablet=&#8221;&#8221; header_2_font_size_phone=&#8221;30px&#8221; header_2_font_size_last_edited=&#8221;on|phone&#8221; global_colors_info=&#8221;{}&#8221;]<\/p>\n<h2>What is PICSI?<\/h2>\n<p>[\/et_pb_text][et_pb_text _builder_version=&#8221;4.16&#8243; text_font=&#8221;Montserrat|300|||||||&#8221; text_line_height=&#8221;2em&#8221; link_font=&#8221;||||||||&#8221; ul_font=&#8221;||||||||&#8221; ol_font=&#8221;||||||||&#8221; quote_font=&#8221;||||||||&#8221; header_font=&#8221;||||||||&#8221; header_2_font=&#8221;Montserrat|300|||||||&#8221; header_2_text_color=&#8221;#212d3b&#8221; header_2_font_size=&#8221;40px&#8221; header_2_line_height=&#8221;1.5em&#8221; max_width=&#8221;100%&#8221; max_width_tablet=&#8221;100%&#8221; max_width_phone=&#8221;&#8221; max_width_last_edited=&#8221;on|tablet&#8221; custom_margin=&#8221;|||&#8221; custom_margin_tablet=&#8221;0px|50px||50px&#8221; custom_margin_last_edited=&#8221;off|desktop&#8221; custom_padding=&#8221;|||&#8221; global_colors_info=&#8221;{}&#8221;]<\/p>\n<p>The PICSI method is a physiological variation on the ICSI technique (sperm microinjection), which is performed using hyaluronic acid (HA).  Hyaluronic acid is involved in the sperm selection mechanism: only mature spermatozoids that have their specific receptors out can bind to the HA around the outer membrane of the egg and fertilise it.<\/p>\n<p>With traditional ICSI, sperm selection is performed by embryologist observation. Physiological ICSI, or PICSI, is less subjective and helps to optimise the results of assisted reproduction treatment.<\/p>\n<p>[\/et_pb_text][\/et_pb_column][et_pb_column type=&#8221;1_2&#8243; _builder_version=&#8221;4.16&#8243; custom_padding=&#8221;|||&#8221; global_colors_info=&#8221;{}&#8221; custom_padding__hover=&#8221;|||&#8221;][et_pb_image src=&#8221;http:\/\/urecentrogutenberg.es\/wp-content\/uploads\/2020\/12\/picsi-ure-centro-gutenberg.jpg&#8221; alt=&#8221;PICSI (Sperm Low) | URE Centro Gutenberg&#8221; title_text=&#8221;PICSI (Sperm Low) | URE Centro Gutenberg&#8221; force_fullwidth=&#8221;on&#8221; align_tablet=&#8221;center&#8221; align_phone=&#8221;&#8221; align_last_edited=&#8221;on|desktop&#8221; _builder_version=&#8221;4.16&#8243; custom_margin=&#8221;|||&#8221; custom_padding=&#8221;|||&#8221; animation_style=&#8221;slide&#8221; animation_direction=&#8221;right&#8221; animation_intensity_slide=&#8221;5%&#8221; border_radii=&#8221;off|0.4vw|0vw|0vw|16vw&#8221; border_color_all=&#8221;rgba(160,208,211,0.35)&#8221; border_width_bottom=&#8221;1.6vw&#8221; border_color_bottom=&#8221;#7ec4d5&#8243; border_color_left=&#8221;rgba(77,185,211,0.6)&#8221; border_radii_last_edited=&#8221;off|desktop&#8221; border_width_all_tablet=&#8221;&#8221; border_width_all_phone=&#8221;&#8221; border_width_all_last_edited=&#8221;on|phone&#8221; box_shadow_style=&#8221;preset3&#8243; box_shadow_vertical=&#8221;30px&#8221; box_shadow_blur=&#8221;80px&#8221; box_shadow_spread=&#8221;-30px&#8221; box_shadow_color=&#8221;rgba(102,141,186,0.7)&#8221; global_colors_info=&#8221;{}&#8221; border_radii__hover_enabled=&#8221;off|desktop&#8221;][\/et_pb_image][\/et_pb_column][\/et_pb_row][\/et_pb_section][et_pb_section fb_built=&#8221;1&#8243; custom_padding_last_edited=&#8221;on|phone&#8221; admin_label=&#8221;Services&#8221; _builder_version=&#8221;4.16&#8243; background_color=&#8221;#eef7f9&#8243; custom_padding=&#8221;3vw|0px|3vw|0px|true|false&#8221; custom_padding_tablet=&#8221;5vw|0px|5vw|0px|true|false&#8221; custom_padding_phone=&#8221;10vw||10vw||true|false&#8221; locked=&#8221;off&#8221; global_colors_info=&#8221;{}&#8221;][et_pb_row _builder_version=&#8221;4.16&#8243; width=&#8221;90%&#8221; max_width=&#8221;1024px&#8221; module_alignment=&#8221;center&#8221; custom_padding=&#8221;4px||0px|||&#8221; global_colors_info=&#8221;{}&#8221;][et_pb_column type=&#8221;4_4&#8243; _builder_version=&#8221;4.16&#8243; custom_padding=&#8221;|||&#8221; global_colors_info=&#8221;{}&#8221; custom_padding__hover=&#8221;|||&#8221;][et_pb_text _builder_version=&#8221;4.16&#8243; text_font=&#8221;Montserrat|300|||||||&#8221; text_line_height=&#8221;1.8em&#8221; header_font=&#8221;||||||||&#8221; header_2_font=&#8221;|300|||||||&#8221; header_2_font_size=&#8221;40px&#8221; header_2_line_height=&#8221;1.5em&#8221; max_width=&#8221;90%&#8221; max_width_tablet=&#8221;100%&#8221; max_width_phone=&#8221;&#8221; max_width_last_edited=&#8221;on|tablet&#8221; module_alignment=&#8221;center&#8221; custom_margin=&#8221;|||&#8221; custom_padding=&#8221;|||&#8221; header_2_font_size_tablet=&#8221;&#8221; header_2_font_size_phone=&#8221;30px&#8221; header_2_font_size_last_edited=&#8221;on|desktop&#8221; global_colors_info=&#8221;{}&#8221;]<\/p>\n<h2>When is PICSI (Sperm Low) indicated?<\/h2>\n<p>[\/et_pb_text][et_pb_text _builder_version=&#8221;4.16&#8243; text_font=&#8221;Montserrat|300|||||||&#8221; text_line_height=&#8221;2em&#8221; link_font=&#8221;||||||||&#8221; ul_font=&#8221;||||||||&#8221; ol_font=&#8221;||||||||&#8221; quote_font=&#8221;||||||||&#8221; header_font=&#8221;||||||||&#8221; header_2_font=&#8221;Montserrat|300|||||||&#8221; header_2_text_color=&#8221;#212d3b&#8221; header_2_font_size=&#8221;40px&#8221; header_2_line_height=&#8221;1.5em&#8221; max_width=&#8221;90%&#8221; max_width_tablet=&#8221;100%&#8221; max_width_phone=&#8221;&#8221; max_width_last_edited=&#8221;on|tablet&#8221; module_alignment=&#8221;center&#8221; custom_margin=&#8221;|28px||||&#8221; custom_padding=&#8221;|||&#8221; global_colors_info=&#8221;{}&#8221;]<\/p>\n<p>PICSI is very useful in patients with high sperm DNA fragmentation but good sperm motility, as the technique helps to select the best quality mature spermatozoids.<\/p>\n<p>These spermatozoids are individually selected and have low fragmentation levels, thus decreasing the likelihood of chromosome abnormalities.<\/p>\n<p>Keeping in mind that this is an experimental technique which is still being researched, it is difficult to determine which patients it is indicated for. But, generally speaking, it is indicated in the following cases:<\/p>\n<p>[\/et_pb_text][\/et_pb_column][\/et_pb_row][et_pb_row column_structure=&#8221;1_2,1_2&#8243; _builder_version=&#8221;4.16&#8243; max_width=&#8221;920px&#8221; module_alignment=&#8221;center&#8221; custom_padding=&#8221;45px||0px||false|false&#8221; global_colors_info=&#8221;{}&#8221;][et_pb_column type=&#8221;1_2&#8243; _builder_version=&#8221;4.16&#8243; custom_padding=&#8221;|||&#8221; global_colors_info=&#8221;{}&#8221; custom_padding__hover=&#8221;|||&#8221;][et_pb_blurb title=&#8221;Elevated sperm DNA fragmentation levels&#8221; use_icon=&#8221;on&#8221; font_icon=&#8221;&#x4e;||divi||400&#8243; icon_color=&#8221;#ffffff&#8221; image_icon_background_color=&#8221;#4db9d3&#8243; icon_placement=&#8221;left&#8221; image_icon_width=&#8221;13px&#8221; content_max_width=&#8221;100%&#8221; _builder_version=&#8221;4.16&#8243; header_font=&#8221;Montserrat||||||||&#8221; header_text_color=&#8221;#5b5b5f&#8221; header_font_size=&#8221;16px&#8221; 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_builder_version=&#8221;4.16&#8243; custom_padding=&#8221;|||&#8221; global_colors_info=&#8221;{}&#8221; custom_padding__hover=&#8221;|||&#8221;][et_pb_text _builder_version=&#8221;4.16&#8243; text_font=&#8221;Montserrat|300|||||||&#8221; text_line_height=&#8221;1.8em&#8221; header_font=&#8221;||||||||&#8221; header_2_font=&#8221;|300|||||||&#8221; header_2_font_size=&#8221;40px&#8221; header_2_line_height=&#8221;1.5em&#8221; max_width=&#8221;90%&#8221; max_width_tablet=&#8221;100%&#8221; max_width_phone=&#8221;&#8221; max_width_last_edited=&#8221;on|tablet&#8221; module_alignment=&#8221;center&#8221; custom_margin=&#8221;|||&#8221; custom_padding=&#8221;|||&#8221; header_2_font_size_tablet=&#8221;&#8221; header_2_font_size_phone=&#8221;30px&#8221; header_2_font_size_last_edited=&#8221;on|desktop&#8221; global_colors_info=&#8221;{}&#8221;]<\/p>\n<h2>PICSI (Sperm Low) Procedure<\/h2>\n<p>[\/et_pb_text][et_pb_text _builder_version=&#8221;4.16&#8243; text_font=&#8221;Montserrat|300|||||||&#8221; text_line_height=&#8221;2em&#8221; link_font=&#8221;||||||||&#8221; ul_font=&#8221;||||||||&#8221; ol_font=&#8221;||||||||&#8221; quote_font=&#8221;||||||||&#8221; header_font=&#8221;||||||||&#8221; header_2_font=&#8221;Montserrat|300|||||||&#8221; header_2_text_color=&#8221;#212d3b&#8221; header_2_font_size=&#8221;40px&#8221; header_2_line_height=&#8221;1.5em&#8221; max_width=&#8221;90%&#8221; max_width_tablet=&#8221;100%&#8221; max_width_phone=&#8221;&#8221; max_width_last_edited=&#8221;on|tablet&#8221; module_alignment=&#8221;center&#8221; custom_margin=&#8221;|28px||||&#8221; custom_padding=&#8221;|||&#8221; global_colors_info=&#8221;{}&#8221;]<\/p>\n<p>The sperm sample for PICSI is collected as usual. After sperm capacitation, the spermatozoids are placed on a special slide.<\/p>\n<p>This slide contains drops of a synthetic material which closely resembles the hyaluronic acid that naturally surrounds oocytes. Good quality spermatozoids will bind to these drops, so the embryologist will be able to easily identify them.<\/p>\n<p>Once the spermatozoid has been selected it is aspirated with the microinjection pipette and ICSI is performed as usual.<\/p>\n<p>[\/et_pb_text][\/et_pb_column][\/et_pb_row][\/et_pb_section][et_pb_section fb_built=&#8221;1&#8243; admin_label=&#8221;Footer&#8221; _builder_version=&#8221;4.16&#8243; background_color=&#8221;#289cb9&#8243; custom_padding=&#8221;3vw|0px|3vw|0px|true|false&#8221; top_divider_height=&#8221;660px&#8221; top_divider_flip=&#8221;horizontal&#8221; bottom_divider_style=&#8221;clouds2&#8243; bottom_divider_color=&#8221;rgba(255,255,255,0.08)&#8221; bottom_divider_height=&#8221;600px&#8221; bottom_divider_flip=&#8221;vertical&#8221; global_colors_info=&#8221;{}&#8221;][et_pb_row _builder_version=&#8221;4.16&#8243; global_colors_info=&#8221;{}&#8221;][et_pb_column type=&#8221;4_4&#8243; _builder_version=&#8221;4.16&#8243; custom_padding=&#8221;|||&#8221; global_colors_info=&#8221;{}&#8221; custom_padding__hover=&#8221;|||&#8221;][et_pb_image src=&#8221;http:\/\/urecentrogutenberg.es\/wp-content\/uploads\/2020\/05\/health-icon-10-2.png&#8221; align=&#8221;center&#8221; align_tablet=&#8221;center&#8221; align_phone=&#8221;&#8221; align_last_edited=&#8221;on|desktop&#8221; _builder_version=&#8221;4.16&#8243; locked=&#8221;off&#8221; global_colors_info=&#8221;{}&#8221;][\/et_pb_image][et_pb_text _builder_version=&#8221;4.16&#8243; text_font=&#8221;Montserrat||||||||&#8221; header_font=&#8221;||||||||&#8221; header_2_font=&#8221;Montserrat|300|||||||&#8221; header_2_text_align=&#8221;center&#8221; header_2_font_size=&#8221;50px&#8221; header_2_line_height=&#8221;1.4em&#8221; text_orientation=&#8221;center&#8221; background_layout=&#8221;dark&#8221; header_2_font_size_tablet=&#8221;&#8221; header_2_font_size_phone=&#8221;30px&#8221; header_2_font_size_last_edited=&#8221;on|phone&#8221; header_2_line_height_tablet=&#8221;1.4em&#8221; header_2_line_height_phone=&#8221;&#8221; header_2_line_height_last_edited=&#8221;on|desktop&#8221; global_colors_info=&#8221;{}&#8221;]<\/p>\n<h2>More info<\/h2>\n<p>Complete the form or call us at (+34) 952 122 565.[\/et_pb_text][wpforms_selector form_id=&#8221;35733&#8243; module_class=&#8221;pedircitaform&#8221; _builder_version=&#8221;4.13.0&#8243; _module_preset=&#8221;default&#8221; global_colors_info=&#8221;{}&#8221;][\/wpforms_selector][\/et_pb_column][\/et_pb_row][\/et_pb_section]<\/p>\n","protected":false},"excerpt":{"rendered":"<p>PICSI (Sperm Low)What is PICSI?The PICSI method is a physiological variation on the ICSI technique (sperm microinjection), which is performed using hyaluronic acid (HA). Hyaluronic acid is involved in the sperm selection mechanism: only mature spermatozoids that have their specific receptors out can bind to the HA around the outer membrane of the egg and [&hellip;]<\/p>\n","protected":false},"author":10,"featured_media":0,"parent":0,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"","meta":{"_et_pb_use_builder":"on","_et_pb_old_content":"","_et_gb_content_width":"","footnotes":""},"class_list":["post-32789","page","type-page","status-publish","hentry"],"_links":{"self":[{"href":"https:\/\/urecentrogutenberg.es\/en\/wp-json\/wp\/v2\/pages\/32789","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/urecentrogutenberg.es\/en\/wp-json\/wp\/v2\/pages"}],"about":[{"href":"https:\/\/urecentrogutenberg.es\/en\/wp-json\/wp\/v2\/types\/page"}],"author":[{"embeddable":true,"href":"https:\/\/urecentrogutenberg.es\/en\/wp-json\/wp\/v2\/users\/10"}],"replies":[{"embeddable":true,"href":"https:\/\/urecentrogutenberg.es\/en\/wp-json\/wp\/v2\/comments?post=32789"}],"version-history":[{"count":0,"href":"https:\/\/urecentrogutenberg.es\/en\/wp-json\/wp\/v2\/pages\/32789\/revisions"}],"wp:attachment":[{"href":"https:\/\/urecentrogutenberg.es\/en\/wp-json\/wp\/v2\/media?parent=32789"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}